Increase Sperm Count Medicines, Natural remedies and dietary modifications may help, but certain drugs can lower sperm count in the long run. A good night's sleep, plenty of water, and avoiding certain drugs can all help men produce more sperm. There is scientific evidence that the antioxidant vitamin C can increase sperm quality and minimize oxidative stress. Traditional Herbal Medicines of Pakistan Maca root, sometimes called Siberian ginseng, is another ingredient that might enhance the quality of your sperm.